Properties
Description
NU6140 is an CDK kinase inhibitor that disrupts cell division processes. It targets Aurora A, Aurora B, CDK1-Cyclin B, and cdk2-cyclin A.
Molecular Formula
C23H30N6O2
Targets
Aurora A: 67 nM; Aurora B: 35 nM; CDK1-Cyclin B: 6.6 μM; cdk2-cyclin A: 0.41 μM
Identity
Confirmed by NMR/HPLC/MS.
Applications
NU6140 can be used to study its inhibition of CDK2, impacting cell cycle regulation and cancer cell proliferation.