Properties
Description
NU6140 is an CDK kinase inhibitor that disrupts cell division processes. It targets Aurora A, Aurora B, CDK1-Cyclin B, and cdk2-cyclin A.
Molecular Formula
C23H30N6O2
Targets
Aurora A: 67 nM; Aurora B: 35 nM; CDK1-Cyclin B: 6.6 μM; cdk2-cyclin A: 0.41 μM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
NU6140 can be used to study its inhibition of CDK2, impacting cell cycle regulation and cancer cell proliferation.