CDK inhibitor PD 0332991 isethionate, Purity ≥98%

Synonym: 827022-33-3; PD0332991; PD-0332991; CDK inhibitor

CAS Number: 827022-33-3
Compound CID: 11478676

Product Size

10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

PD 0332991 isethionate, soluble in DMSO and warmed water and insoluble in ethanol, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK4/CyclinD1, CDK6/CyclinD2, AMPK, and c-Src.

Molecular Weight

573.7

Molecular Formula

C₂₆H₃₅N₇O₆S

Targets

CDK4/CyclinD1: 11 nM; CDK6/CyclinD2: 15 nM; AMPK: >10 μM; c-Src: >10 μM

Form

Lyophilized powder

Purity

Solubility

DMSO: Insoluble; Warmed water: 9 mg/mL (15.69 mM); Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

PD 0332991 isethionate (Palbociclib) can be utilized in research on the selective inhibition of CDK4/6 in cancer.