CDK inhibitor PD0166285, Purity ≥98%

Synonym: 185039-89-8; PD-0166285; PD 0166285; CDK inhibitor

CAS Number: 185039-89-8
Compound CID: 5311382

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PD0166285, soluble in DMSO and ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets Chk1, Myt1, and Wee1.

Molecular Weight

512.43

Molecular Formula

C₂₆H₂₇Cl₂N₅O₂

Targets

Chk1: 3.4 μM; Myt1: 72 nM; Wee1: 24 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 91 mg/mL (177.58 mM); Water: Insoluble; Ethanol: 91 mg/mL (177.58 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

PD0166285 can be used to study its inhibition of CHK1 and its potential in cancer research for overcoming resistance to chemotherapeutic agents.