CDK inhibitor PHA-767491 hydrochloride, Purity ≥98%

Synonym: 942425-68-5; PHA767491; PHA 767491; CAY-10572 hydrochloride; CAY10572; CAY 10572; CDK inhibitor

CAS Number: 942425-68-5
Compound CID: 11715766

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PHA-767491 hydrochloride, soluble in DMSO and insoluble in ethanol and water, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1, CDK2, CDK5, and CDK9.

Molecular Weight

249.7

Molecular Formula

C₁₂H₁₂ClN₃O

Targets

CDK1: 250 nM; CDK2: 240 nM; CDK5: 460 nM; CDK9: 34 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 24 mg/mL (96.11 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

PHA-767491 hydrochloride can be used to explore CDK7 and CDK9 inhibition and its role in cell cycle regulation.