Properties
Description
PHA-793887, soluble in DMSO and ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK2/CyclinA, CDK2/CyclinE, CDK1/CyclinB, and CDK4/CyclinD1.
Molecular Formula
C19H31N5O2
Targets
CDK2/CyclinA: 8 nM; CDK2/CyclinE: 8 nM; CDK1/CyclinB: 60 nM; CDK4/CyclinD1: 62 nM
Solubility
DMSO: 61 mg/mL (168.75 mM); Water: Insoluble; Ethanol: 61 mg/mL (168.75 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
PHA-793887 can be employed in research to study its inhibition of CDKs and its potential in cancer therapy.
