CDK inhibitor Poloxin, Purity ≥98%

Synonym: 321688-88-4; Poloxin; CHEMBL3944542; [(Z)-(2-methyl-4-oxo-5-propan-2-ylcyclohexa-2,5-dien-1-ylidene)amino] 2-methylbenzoate; CDK inhibitor

CAS Number: 321688-88-4
Compound CID: 9613592

Product Size

10 mg; 25 mg; 50 mg; 100mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Poloxin is an CDK kinase inhibitor that disrupts cell division processes. It targets PLK1 PBD, PLK2 PBD, and PLK3 PBD.

Molecular Weight

297.35

Molecular Formula

C₁₈H₁₉NO₃

Targets

PLK1 PBD: 4.8 μM; PLK2 PBD: 18.7 μM; PLK3 PBD: 53.9 μM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Poloxin can be used to investigate the inhibition of Polo-like kinase 1 (Plk1) and its effects on mitotic progression and cancer therapy.

Storage

Store at -20ºC.