CDK inhibitor Purvalanol B, Purity ≥98%

Synonym: 212844-54-7; NG 95; CDK inhibitor

CAS Number: 212844-54-7
Compound CID: 448991

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Purvalanol B, soluble in DMSO, water and ethanol, is an CDK kinase inhibitor that disrupts cell division processes. It targets cdc2/cyclin B, cdk2/cyclin A, CDK2/cyclinE, and CDK5/p35.

Molecular Weight

432.91

Molecular Formula

C₂₀H₂₅ClN₆O₃

Targets

cdc2/cyclin B: 6 nM; cdk2/cyclin A: 6 nM; CDK2/cyclinE: 9 nM; CDK5/p35: 6 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 84 mg/mL (194.04 mM); Water: <1 mg/mL; Ethanol: <1 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Purvalanol B can be used to explore CDK inhibition and its effects on cell cycle arrest and apoptosis.

Storage

Store at -20ºC.