CDK inhibitor RO3280, Purity ≥98%

Synonym: 1062243-51-9; RO 3280; RO-3280; CDK inhibitor

CAS Number: 1062243-51-9
Compound CID: 25015677

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

RO3280, soluble in DMSO and ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets ALK, CAMKK1, CAMKK2, and DAPK1.

Molecular Weight

543.61

Molecular Formula

C₂₇H₃₅F₂N₇O₃

Targets

ALK: 230 nM (Kd); CAMKK1: 1100 nM (Kd); CAMKK2: 87 nM (Kd); DAPK1: 100 nM (Kd)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 87 mg/mL (160.04 mM); Water: Insoluble; Ethanol: 87 mg/mL (160.04 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

RO3280 is used to investigate its ability to inhibit Plk1 and its therapeutic potential in oncology.

Storage

Store at -20ºC.