CDK inhibitor Roscovitine, Purity ≥98%

Synonym: 186692-46-6; CYC202; Seliciclib; CDK inhibitor

CAS Number: 186692-46-6
Compound CID: 160355

Product Size

10 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Roscovitine, soluble in DMSO and ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets Cdc2/CyclinB, CDK2/CyclinA, c-Src, and CDK2/CyclinE.

Molecular Weight

354.5

Molecular Formula

C₁₉H₂₆N₆O

Targets

Cdc2/CyclinB: 0.65 μM; CDK2/CyclinA: 0.7 μM; c-Src: 250 μM; CDK2/CyclinE: 0.7 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 69 mg/mL (194.67 mM); Water: Insoluble; Ethanol: 6 mg/mL (16.92 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Roscovitine is used to investigate its role as a CDK inhibitor and its effects on cell cycle arrest and apoptosis.

Storage

Store at -20ºC.