Properties
Description
SB 218078 is an CDK kinase inhibitor that disrupts cell division processes. It targets Cdc2, Chk1, and PKC.
Molecular Formula
C24H15N3O3
Targets
Cdc2: 250 nM; Chk1: 15 nM; PKC: 1000 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
SB 218078 can be used to study its inhibition of cyclin-dependent kinase 2 (CDK2) and its effects on cell cycle arrest.