CDK inhibitor SBE 13 HCl, Purity ≥98%

Synonym: 1052532-15-6; SBE-13; SBE 13; CDK inhibitor

CAS Number: 1052532-15-6
Compound CID: 11948807

Product Size

10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SBE 13 HCl, soluble in DMSO and insoluble in ethanol and water, is an CDK kinase inhibitor that disrupts cell division processes. It targets PLK1, PLK2, and PLK3.

Molecular Weight

479.4

Molecular Formula

C₂₄H₂₇ClN₂O₄.HCl

Targets

PLK1: 200 pM; PLK2: >66 μM; PLK3: 875 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 90 mg/mL (187.73 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

SBE 13 HCl is employed to study its effects as a selective CHK1 inhibitor and its role in sensitizing cancer cells to DNA-damaging agents.

Storage

Store at -20ºC.