Properties
Description
SCH 900776, soluble in DMSO and insoluble in ethanol and water, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK2, Chk1, and Chk2.
Molecular Formula
C15H18BrN7
Targets
CDK2: 160 nM; Chk1: 3 nM; Chk2: 1500 nM
Solubility
DMSO: 3 mg/mL (7.97 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
SCH 900776 is used to investigate its role as a CHK1 inhibitor and its potential to enhance the efficacy of chemotherapeutic agents.