CDK inhibitor SEL120-34A, Purity ≥98%

Synonym: 1609522-33-9; SEL 120-34A; SEL-120-34A; SEL12034A; SEL 12034A; SEL-12034A; CDK inhibitor

CAS Number: 1609522-33-9
Compound CID: 73776233

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SEL120-34A, soluble in DMSO and water and insoluble in ethanol, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK19/CycC, CDK8/CycC, and CDK9/cycT.

Molecular Weight

414.145

Molecular Formula

C₁₅H₁₈Br₂N₄

Targets

CDK19/CycC: 10.4 nM; CDK8/CycC: 4.4 nM; CDK9/cycT: 1070 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 9 mg/mL (19.97 mM); Water: 77 mg/mL (170.88 mM); Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

SEL120-34A can be employed to study its selective inhibition of CDK8, implicated in cancer and gene transcription.