CDK inhibitor Senexin A, Purity ≥98%

Synonym: 1366002-50-7; Senexin A; 4-(Phenethylamino)quinazoline-6-carbonitrile; CHEMBL4226806; 4-[(2-Phenylethyl)amino]-6-quinazolinecarbonitril; CDK inhibitor

CAS Number: 1366002-50-7
Compound CID: 56927063

Product Size

2 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Senexin A, soluble in DMSO and ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK19 and CDK8.

Molecular Weight

274.32

Molecular Formula

C₁₇H₁₄N₄

Targets

CDK19: 0.31 μM (Kd); CDK8: 0.83 μM (Kd)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 46 mg/mL (167.69 mM; Water: Insoluble; Ethanol: 46 mg/mL (167.69 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

Senexin A can be used to study the inhibition of CDK8 and CDK19-mediated signaling pathways.