Properties
Description
SNS-032, soluble in DMSO and insoluble in ethanol and water, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK2/CyclinA, CDK2/CyclinE, CDK1/CyclinB, and CDK4/CyclinD.
Molecular Formula
C17H24N4O2S2
Targets
CDK2/CyclinA: 38 nM; CDK2/CyclinE: 48 nM; CDK1/CyclinB: 480 nM; CDK4/CyclinD: 925 nM
Solubility
DMSO: 74 mg/mL (194.46 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
SNS-032 is used to explore its inhibitory activity against CDK2, CDK7, and CDK9, and its implications for cancer treatment.