Properties
Description
SU9516, soluble in DMSO and warmed ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1, CDK4, CDK2, and EGFR.
Molecular Formula
C13H11N3O2
Targets
CDK1: 40 nM; CDK4: 200 nM; CDK2: 22 nM; EGFR: >100 μM
Solubility
DMSO: 44 mg/mL (182.38 mM); Water: Insoluble; Warmed ethanol: 11 mg/mL (45.6 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
SU9516 can be used to explore the selective inhibition of CDK2, CDK5, and CDK9 in cancer research.
