Properties
Description
TG003, soluble in warmed DMSO and insoluble in water and ethanol, is an CDK kinase inhibitor that disrupts cell division processes. It targets CLK1, CLK2, and CLK4.
Molecular Formula
C13H15NO2S
Targets
CLK1: 20 nM; CLK2: 200 nM; CLK4: 15 nM
Solubility
Warmed DMSO: 5 mg/mL (20.05 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
TG003 can be used to study the inhibition of Cdc2-like kinases (CLKs) and their effects on pre-mRNA splicing.