Properties
Description
Voruciclib hydrochloride is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1/cyc A, CDK1/cycB, CDK4/Cyc D1, and CDK6/cycD1.
Molecular Formula
C22H20Cl2F3NO5
Targets
CDK1/cyc A: 9.1 nM (Ki); CDK1/cycB: 5.4 nM (Ki); CDK4/Cyc D1: 3.96 nM (Ki); CDK6/cycD1: 2.92 nM (Ki)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Voruciclib hydrochloride is used to investigate the inhibition of CDK9 and its effects on transcription regulation in cancer cells.