Properties
Description
Voruciclib hydrochloride is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1/cyc A, CDK1/cycB, CDK4/Cyc D1, and CDK6/cycD1.
Molecular Formula
C22H20Cl2F3NO5
Targets
CDK1/cyc A: 9.1 nM (Ki); CDK1/cycB: 5.4 nM (Ki); CDK4/Cyc D1: 3.96 nM (Ki); CDK6/cycD1: 2.92 nM (Ki)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Voruciclib hydrochloride is used to investigate the inhibition of CDK9 and its effects on transcription regulation in cancer cells.