Properties
Description
CFTRinh-172, soluble in DMSO and insoluble in ethanol and water, blocks the activity of the cystic fibrosis transmembrane conductance regulator protein, which plays a crucial role in the movement of chloride ions across cell membranes. It targets CFTR.
Molecular Formula
C18H10F3NO3S2
Targets
CFTR: 300 nM (Ki)
Solubility
DMSO: 71 mg/mL (173.42 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Known as a CFTR inhibitor, CFTRinh-172 is used extensively in studies related to chloride ion transport and cystic fibrosis.
