CFTR inhibitor GLPG1837, Purity ≥98%

Synonym: 1654725-02-6; CFTR inhibitor; GLPG 1837; GLPG-1837; ABBV-974; ABBV 974; ABBV974

CAS Number: 1654725-02-6
Compound CID: 117857370

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GLPG1837, soluble in DMSO and ethanol and insoluble in water, blocks the activity of the cystic fibrosis transmembrane conductance regulator protein, which plays a crucial role in the movement of chloride ions across cell membranes.

Molecular Weight

348.42

Molecular Formula

C₁₆H₂₀N₄O₃S

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 68 mg/mL (195.16 mM); Water: Insoluble; Ethanol: 5 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

GLPG1837 serves to study and inhibit CFTR channels, significant in cystic fibrosis research.