CFTR-inhibitor-II, Purity ≥98%

Synonym: 328541-79-3; CFTR-inhibitor; GlyH-101; Cystic Fibrosis Transmembrane Conductance; Regulator Inhibitor II

CAS Number: 328541-79-3
Compound CID: 135476586

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

CFTR-inhibitor-II, soluble in DMSO and insoluble in ethanol and water, blocks the activity of the cystic fibrosis transmembrane conductance regulator protein, which plays a crucial role in the movement of chloride ions across cell membranes. It targets CFTR.

Molecular Weight

493.2

Molecular Formula

C₁₉H₁₅Br₂N₃O₃

Targets

CFTR: 4.3 μM (Ki)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 91 mg/mL (184.53 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

CFTR-inhibitor-II is used to inhibit the CFTR channel, crucial for cystic fibrosis research.