Properties
Description
IOWH032, soluble in DMSO and insoluble in ethanol and water, blocks the activity of the cystic fibrosis transmembrane conductance regulator protein, which plays a crucial role in the movement of chloride ions across cell membranes. It targets CFTR.
Molecular Formula
C22H15Br2N3O4
Solubility
DMSO: 88 mg/mL (161.41 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
IOWH032 is applied to inhibit CFTR, aiding studies on cystic fibrosis and related chloride ion transport dysfunctions.
