Properties
Description
KM 11060, soluble in DMSO and ethanol and insoluble in water, blocks the activity of the cystic fibrosis transmembrane conductance regulator protein, which plays a crucial role in the movement of chloride ions across cell membranes.
Molecular Formula
C19H17Cl2N3O2S
Solubility
DMSO: 81 mg/mL (191.79 mM); Water: Insoluble; Ethanol: 2 mg/mL (4.73 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
KM 11060 is utilized in research as a CFTR inhibitor, often to study cystic fibrosis and chloride ion transport mechanisms.
