Properties
Description
PPQ-102, soluble in DMSO and insoluble in ethanol and water, blocks the activity of the cystic fibrosis transmembrane conductance regulator protein, which plays a crucial role in the movement of chloride ions across cell membranes.
Molecular Formula
C26H22N4O3
Solubility
DMSO: 48 mg/mL (109.47 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
PPQ-102 serves as a CFTR inhibitor explored in research on cystic fibrosis and related chloride transport mechanisms.