Properties
Description
PTI-428, soluble in DMSO and insoluble in ethanol and water, blocks the activity of the cystic fibrosis transmembrane conductance regulator protein, which plays a crucial role in the movement of chloride ions across cell membranes.
Molecular Formula
C18H18N4O4
Solubility
DMSO: 65 mg/mL (183.43 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
PTI-428 is utilized in research to inhibit CFTR channels, relevant in treating cystic fibrosis.
