Properties
Description
Cimifugin is a bioactive component of Cimicifuga racemosa, a Chinese herb. Cimifugin suppresses allergic inflammation by reducing epithelial-derived initiative key factors via regulating tight junctions. Cimifugin reduces the migration and chemotaxis of RAW264.7 cells and inhibits the release of inflammatory factors and activation of MAPKs and NF-κB signaling pathways induced by LPS.
Molecular Formula
C16H18O6
Source
Rhizome of Cimicifnga foetida L
Purity
>98%, determined by HPLC.
Solubility
It is soluble in methanol, DMSO, insoluble in petroleum ether.
Identity
Confirmed by NMR and MS.
Applications
Cimifugin can be used for improving immunity, inhibiting nucleoside translocation, and antitumor activity experiments, etc.
