Properties
Description
Clemastine fumarate, soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets histamine H1 receptor.
Molecular Formula
C21H26ClNO·C4H4O4
Targets
Histamine H1 receptor: 3 nM
Solubility
DMSO: 31 mg/mL (67.39 mM); Water: insoluble; Ethanol: insoluble
Applications
Clemastine fumarate can be used to alleviate symptoms of allergic conjunctivitis, which is inflammation of the conjunctiva.