Properties
Description
Clemastine fumarate, soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets histamine H1 receptor.
Molecular Formula
C21H26ClNO·C4H4O4
Targets
Histamine H1 receptor: 3 nM
Solubility
DMSO: 31 mg/mL (67.39 mM); Water: insoluble; Ethanol: insoluble
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Clemastine fumarate can be used to alleviate symptoms of allergic conjunctivitis, which is inflammation of the conjunctiva.
Storage
Store at -20℃, and keep desiccated.
