Properties
Description
Clodronate disodium, insoluble in DMSO and ethanol and soluble in water, is the disodium salt of a nitrogen-free bisphosphonate analog of naturally occurring pyrophosphate. The molecular weight of the compound is 288.86, and its molecular formula is CH2Cl2Na2O6P2.
Molecular Formula
CH2Cl2Na2O6P2
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: insoluble; Water: 66 mg/mL (228.48 mM); Ethanol: insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Clodronate disodium plays a key role in preventing hypercalcemia.