Properties
Description
Acemetacin, soluble in DMSO and warmed ethanol and insoluble in water, blocks the COX enzymes from converting arachidonic acid to prostaglandins, thereby reducing inflammatory reactions.
Molecular Formula
C21H18ClNO6
Solubility
DMSO: 82 mg/mL (197.2 mM); Water: Insoluble; Warmed ethanol: 57 mg/mL (137.08 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Acemetacin can be used to explore its anti-inflammatory effects in conditions such as osteoarthritis and rheumatoid arthritis.