Properties
Description
Acemetacin, soluble in DMSO and warmed ethanol and insoluble in water, blocks the COX enzymes from converting arachidonic acid to prostaglandins, thereby reducing inflammatory reactions.
Molecular Formula
C21H18ClNO6
Solubility
DMSO: 82 mg/mL (197.2 mM); Water: Insoluble; Warmed ethanol: 57 mg/mL (137.08 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Acemetacin can be used to explore its anti-inflammatory effects in conditions such as osteoarthritis and rheumatoid arthritis.