Properties
Description
Diflunisal, soluble in DMSO and ethanol and insoluble in water, blocks the COX enzymes from converting arachidonic acid to prostaglandins, thereby reducing inflammatory reactions. It targets cyclooxygenase and p300.
Molecular Formula
C13H8F2O3
Targets
cyclooxygenase; p300: 996 μM
Solubility
DMSO: 47 mg/mL (187.85 mM); Water: Insoluble; Ethanol: 19 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Diflunisal is studied for its non-steroidal anti-inflammatory and analgesic properties, making it relevant in pain and inflammation research.