Properties
Description
Nimesulide, soluble in DMSO and insoluble in ethanol and water, blocks the COX enzymes from converting arachidonic acid to prostaglandins, thereby reducing inflammatory reactions. It targets COX2.
Molecular Formula
C13H12N2O5S
Solubility
DMSO: 55 mg/mL (178.39 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Nimesulide can be used to study its selective COX-2 inhibition in pain and inflammation management.