Properties
Description
NS-398, soluble in DMSO and insoluble in ethanol and water, blocks the COX enzymes from converting arachidonic acid to prostaglandins, thereby reducing inflammatory reactions.
Molecular Formula
C13H18N2O5S
Solubility
DMSO: 53 mg/mL (168.59 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
NS-398 can be used to study its specific inhibition of COX-2 in inflammation and cancer.