COX inhibitor S-2474, Purity ≥98%

Synonym: 158089-95-3; S-2474; CHEMBL291543; 2,6-Ditert-butyl-4-[(E)-(2-ethyl-1,1-dioxo-1,2-thiazolidin-5-ylidene)methyl]phenol; PHENOL, 2,6-BIS(1,1-DIMETHYLETHYL)-4-[(E)-(2-ETHYL-1,1-DIOXIDO-5-ISOTHIAZOLIDINYLIDENE)METHYL]-; SCHEMBL27029; COX inhibitor

CAS Number: 158089-95-3
Compound CID: 9907157

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

S-2474 blocks the COX enzymes from converting arachidonic acid to prostaglandins, thereby reducing inflammatory reactions. It targets 5-LO, COX-1, and COX-2.

Molecular Weight

365.53

Molecular Formula

C₂₀H₃₁NO₃S

Targets

5-LO; COX-1: 27 μM; COX-2: 11 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

S-2474 is a selective COX-2 inhibitor used to study the role of COX-2 in inflammation and pain.

Storage

Store at -20ºC.