COX inhibitor TFAP, Purity ≥98%

Synonym: TFAP; 1011244-68-0; N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide; COX-1 Inhibitor IVTFAP; CHEMBL409023; COX inhibitor

MDL: MFCD12463359
CAS Number: 1011244-68-0
Compound CID: 24752865

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

TFAP, soluble in DMSO and ethanol and insoluble in water, blocks the COX enzymes from converting arachidonic acid to prostaglandins, thereby reducing inflammatory reactions. It targets COX1.

Molecular Weight

281.23

Molecular Formula

C₁₃H₁₀F₃N₃O

Targets

COX1: 0.8 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 55 mg/mL (195.56 mM); Water: Insoluble; Ethanol: 55 mg/mL (195.56 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

TFAP can be employed to examine the function and inhibition of the transcription factor activator protein-1 (AP-1) in various cellular processes.