Cat. No.: X24-09-YM521
CRM1 inhibitor, Leptomycin B, Purity ≥98%
Synonym: 87081-35-4; CI 940; CI940; CI-940; LMB; (2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-17-Ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-19-[(2S,3S)-3-methyl-6-oxo-2,3-dihydropyran-2-yl]-8-oxononadeca-2,10,12,16,18-pentaenoic acid; CRM1 inhibitor
- MDL: MFCD06795848
- CAS Number: 87081-35-4
- Compound CID: 6917907
Product Size
1 mg; 5 mg; 10 mg; 20 mg
Properties
Description
Leptomycin B is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of membrane transporters-ion channels by inhibiting CRM1. The molecular weight of the compound is 540.73, and its molecular formula is C33H48O6.
Molecular Formula
C33H48O6
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Identity
Confirmed by NMR/HPLC/MS.
Applications
Leptomycin B can be used for its anti-cancer properties, particularly in leukemia and solid tumors, by promoting apoptosis and cell cycle arrest.
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