Properties
Description
BLZ945, soluble in DMSO and warmed ethanol and insoluble in water, inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis. It targets CSF-1R.
Molecular Formula
C20H22N4O3S
Solubility
DMSO: 77 mg/mL (193.23 mM); Water: Insoluble; Warmed ethanol: 3 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
BLZ945 is used to investigate macrophage-related mechanisms in cancer and inflammatory research, highlighting its therapeutic potential.
