Properties
Description
GW2580, soluble in DMSO and insoluble in ethanol and water, inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis.
Molecular Formula
C20H22N4O3
Solubility
DMSO: 48 mg/mL (131 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
GW2580 is used to inhibit CSF-1R in macrophage studies, which aids in understanding its role in cancer and inflammatory diseases.
