Properties
Description
JTE-952 inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis.
Molecular Formula
C30H34N2O6
Identity
Confirmed by NMR/HPLC/MS.
Applications
JTE-952 is used to investigate the CSF-1R pathway, which plays a critical role in macrophage survival and proliferation, thereby advancing understanding of immune response modulation.