Properties
Description
PLX5622, soluble in DMSO and insoluble in ethanol and water, inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis.
Molecular Formula
C21H19F2N5O
Solubility
DMSO: 71 mg/mL (179.56 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
PLX5622 is employed in research to explore its effects on microglia and macrophages, offering insight into neuroinflammatory and neurodegenerative disease processes.
