Properties
Description
Plerixafor 8HCl, soluble in water and insoluble in DMSO and ethanol, is a chemokine receptor-4 antagonist. It targets CXCL12 mediated chemotaxis and CXCR4.
Molecular Formula
C28H54N8.8HCl
Targets
CXCL12 mediated chemotaxis: 5.7 nM; CXCR4: 44 nM
Solubility
DMSO: Insoluble; Water: 91 mg/mL (114.54 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Plerixafor 8HCl can be used to investigate its use as a hematopoietic stem cell mobilizer in cancer therapy.