CXCR inhibitor AMD 070, Purity ≥98%

Synonym: AMD-070; 558447-26-0; Mavorixafor; (S)-N1-((1H-Benzo[d]imidazol-2-yl)methyl)-N1-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine; CXCR inhibitor

MDL: MFCD11977316
CAS Number: 558447-26-0
Compound CID: 11256587

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AMD 070 is an active small molecule compound that mediates the CXCR signaling pathway. It targets 125I-SDF-CXCR4, HIV1 (NL4.3 strain), HIV1 (NL4.3 strain), HIV-1 (NL4.3 strain), and HIV-1 (NL4.3 strain).

Molecular Weight

349.5

Molecular Formula

C₂₁H₂₇N₅

Targets

125I-SDF-CXCR4: 13 nM; HIV1 (NL4.3 strain): 1 nM (In MT4 cells); HIV1 (NL4.3 strain): 9 nM (In PBMCs); HIV-1 (NL4.3 strain): 3 nM (In MT-4 cells); HIV-1 (NL4.3 strain): 26 nM (In PBMCs) :

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

AMD 070 can be used to study its function as an HIV entry inhibitor targeting the CXCR4 receptor.