CXCR inhibitor AMD 070, Purity ≥98%

Synonym: AMD-070; 558447-26-0; Mavorixafor; (S)-N1-((1H-Benzo[d]imidazol-2-yl)methyl)-N1-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine; CXCR inhibitor

MDL: MFCD11977316
CAS Number: 558447-26-0
Compound CID: 11256587

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AMD 070 is an active small molecule compound that mediates the CXCR signaling pathway. It targets 125I-SDF-CXCR4, HIV1 (NL4.3 strain), HIV1 (NL4.3 strain), HIV-1 (NL4.3 strain), and HIV-1 (NL4.3 strain).

Molecular Weight

349.5

Molecular Formula

C₂₁H₂₇N₅

Targets

125I-SDF-CXCR4: 13 nM; HIV1 (NL4.3 strain): 1 nM (In MT4 cells); HIV1 (NL4.3 strain): 9 nM (In PBMCs); HIV-1 (NL4.3 strain): 3 nM (In MT-4 cells); HIV-1 (NL4.3 strain): 26 nM (In PBMCs) :

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

AMD 070 can be used to study its function as an HIV entry inhibitor targeting the CXCR4 receptor.

Storage

Store at -20ºC.