CXCR inhibitor AMD3100, Purity ≥98%

Synonym: Plerixafor; 110078-46-1; Mozobil; AMD3100; 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene; Amd 3100; CXCR inhibitor

MDL: MFCD05662218
CAS Number: 110078-46-1
Compound CID: 65015

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AMD3100, soluble in warmed water and ethanol and insoluble in DMSO, targets the chemokine receptors CXCR, which are part of the GPCR family. It targets CXCL12 mediated chemotaxis and CXCR4.

Molecular Weight

502.78

Molecular Formula

C₂₈H₅₄N₈

Targets

CXCL12 mediated chemotaxis: 5.7 nM; CXCR4: 44 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: Insoluble; Warmed water: 3 mg/mL (5.96 mM); Ethanol: 86 mg/mL (171.05 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

AMD3100 can be used to investigate its effects as a CXCR4 antagonist in stem cell mobilization and HIV research.

Storage

Store at -20ºC.