CXCR inhibitor AZD-5069, Purity ≥98%

Synonym: AZD-5069; 878385-84-3; AZD5069; N-(2-((2,3-Difluorobenzyl)thio)-6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)pyrimidin-4-yl)azetidine-1-sulfonamide; 4ADT8JXB9S; AZD 5069 [WHO-DD]; N-(2-(((2,3-Difluorophenyl)methyl)thio)-6-(((1R,2S)-2,3-dihydroxy-1-methylpropyl)oxy)-4-pyrimidinyl)-1-azetidinesulfonamide; CXCR inhibitor

CAS Number: 878385-84-3
Compound CID: 56645576

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AZD-5069, soluble in DMSO and ethanol and insoluble in water, targets the chemokine receptors CXCR, which are part of the GPCR family. It targets 125I-IL8-CXCR2.

Molecular Weight

476.51

Molecular Formula

C₁₈H₂₂F₂N₄O₅S₂

Targets

125I-IL8-CXCR2

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 81 mg/mL (169.98 mM); Water: Insoluble; Ethanol: 6 mg/mL (12.58 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

AZD-5069 is a selective CXCR2 antagonist used in oncology and inflammatory disease research to study neutrophil recruitment.

Storage

Store at -20ºC.