Cat. No.: X23-10-ZQ629
CXCR inhibitor AZD-5069, Purity ≥98%
Synonym: AZD-5069; 878385-84-3; AZD5069; N-(2-((2,3-Difluorobenzyl)thio)-6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)pyrimidin-4-yl)azetidine-1-sulfonamide; 4ADT8JXB9S; AZD 5069 [WHO-DD]; N-(2-(((2,3-Difluorophenyl)methyl)thio)-6-(((1R,2S)-2,3-dihydroxy-1-methylpropyl)oxy)-4-pyrimidinyl)-1-azetidinesulfonamide; CXCR inhibitor
- CAS Number: 878385-84-3
- Compound CID: 56645576
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
AZD-5069, soluble in DMSO and ethanol and insoluble in water, targets the chemokine receptors CXCR, which are part of the GPCR family. It targets 125I-IL8-CXCR2.
Molecular Formula
C18H22F2N4O5S2
Solubility
DMSO: 81 mg/mL (169.98 mM); Water: Insoluble; Ethanol: 6 mg/mL (12.58 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
AZD-5069 is a selective CXCR2 antagonist used in oncology and inflammatory disease research to study neutrophil recruitment.
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