CXCR inhibitor NBI-74330, Purity ≥98%

Synonym: 855527-92-3; NBI-74330; 473722-68-8; N-[1-[3-(4-Ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-(pyridin-3-ylmethyl)acetamide; CXCR inhibitor

CAS Number: 855527-92-3
Compound CID: 10167713

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

NBI-74330 targets the chemokine receptors CXCR, which are part of the GPCR family. It targets 125I-CXCL10-CXCR3 and 125I-CXCL11-CXCR3.

Molecular Weight

605.58

Molecular Formula

C₃₂H₂₇F₄N₅O₃

Targets

125I-CXCL10-CXCR3: 1.5 nM (Ki, in CXCR3CHO cell membranes); 125I-CXCL11-CXCR3: 3.2 nM (Ki, in CXCR3CHO cell membranes)

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

NBI-74330 is a neurokinin-1 receptor antagonist used to study its role in pain and psychiatric disorders.

Storage

Store at -20ºC.