Properties
Description
Reparixin L-lysine salt targets the chemokine receptors CXCR, which are part of the GPCR family. It targets CXCR1, CXCR1-Ile43Val, CXCR1-wt, and CXCR2.
Molecular Formula
C20H35N3O5S
Targets
CXCR1: 1 nM; CXCR1-Ile43Val: 80 nM (In L1.2 cells); CXCR1-wt: 5.6 nM (In L1.2 cells); CXCR2: 100 nM (In cells)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Reparixin L-lysine salt can be utilized in research exploring its inhibition of CXCR1/2 in inflammation and ischemia-reperfusion injury.