CXCR inhibitor Reparixin, Purity ≥98%

Synonym: Reparixin; 266359-83-5; DF 1681Y; (R)-2-(4-Isobutylphenyl)-N-(methylsulfonyl)propanamide; DF1681Y; Reparixin (Repertaxin); CXCR inhibitor

MDL: MFCD18633292
CAS Number: 266359-83-5
Compound CID: 9838712

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Reparixin, soluble in DMSO and ethanol and insoluble in water, targets the chemokine receptors CXCR, which are part of the GPCR family. It targets CXCR1, CXCR1-Ile43Val, CXCR1-wt, and CXCR2.

Molecular Weight

283.39

Molecular Formula

C₁₄H₂₁NO₃S

Targets

CXCR1: 1 nM; CXCR1-Ile43Val: 80 nM (In L1.2 cells); CXCR1-wt: 5.6 nM (In L1.2 cells); CXCR2: 100 nM (In cells)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 52 mg/mL (183.49 mM); Water: Insoluble; Ethanol: 52 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

Reparixin can be used to study its effects as a CXCR1/2 inhibitor in inflammation and cancer research.