CXCR inhibitor SB225002, Purity ≥98%

Synonym: 182498-32-4; sb 225002; SB225002; 1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea; SB-225002; N-(2-Bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)urea; CHEMBL239767; CXCR inhibitor

MDL: MFCD00954637
CAS Number: 182498-32-4
Compound CID: 3854666

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SB225002, soluble in DMSO and warmed ethanol and insoluble in water, targets the chemokine receptors CXCR, which are part of the GPCR family. It targets CXCR2.

Molecular Weight

352.14

Molecular Formula

C₁₃H₁₀BrN₃O₄

Targets

CXCR2: 22 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 64 mg/mL (181.74 mM); Water: Insoluble; Warmed ethanol: 3 mg/mL (8.51 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

SB225002 can be used to study its antagonistic effects on the CXCR2 receptor in neutrophil trafficking and inflammation.

Storage

Store at -20ºC.