Properties
Description
SCH 563705 targets the chemokine receptors CXCR, which are part of the GPCR family. It targets CXCR1, CXCR1, CXCR2, CXCR2, and mouse CXCR2.
Molecular Formula
C23H27N3O5
Targets
CXCR1: 3 nM (Ki); CXCR1: 7.3 nM; CXCR2: 1 nM (Ki); CXCR2: 1.3 nM; Mouse CXCR2: 5.2 nM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
SCH 563705 can be applied in research targeting CXCR3 antagonism in autoimmune and inflammatory conditions.