Properties
Description
E-64, soluble in warmed DMSO and warmed water and insoluble in ethanol, obstructs cysteine proteases, enzymes implicated in numerous diseases due to their role in protein degradation. It targets Cysteine protease.
Molecular Formula
C15H27N5O5
Targets
Cysteine protease: 9 nM
Solubility
Warmed DMSO: 61 mg/mL (170.67 mM); Warmed water: 9 mg/mL (25.18 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
E-64 is a cysteine protease inhibitor used to study and inhibit proteases like cathepsins, facilitating research in degenerative diseases and cancer.