Properties
Description
MK-0822, soluble in DMSO and insoluble in ethanol and water, obstructs cysteine proteases, enzymes implicated in numerous diseases due to their role in protein degradation. It targets Cathepsin K (human) and Cathepsin K (rabbit).
Molecular Formula
C25H27F4N3O3S
Targets
Cathepsin K (human): 0.2 nM; Cathepsin K (rabbit): 1 nM
Solubility
DMSO: 96 mg/mL (182.66 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
MK-0822 inhibits effects on cysteine proteases, enzymes linked to bone resorption conditions like osteoporosis.